Guidelines for care
increasingly help guide medical decision-making. If you’ve followed top health
news over the past several years you’ve read conflicting statements about the
utility of various medical procedures and tests. As a general internist I’ve
devoured these reports with particular interest trying to wade through bias to
formulate views that I believe will be of most benefit to my patients.
Recently I put together a talk about recommendations for prevention in women. As I prepared the talk I sorted through the data and opinions of various medical special interest groups. Guidelines for care are usually developed by professional organizations or “expert panels,” such as the Center for Disease Control (CDC), or the American Cancer Society (ACS). One might like to think of these panels as unbiased in their advice, but clearly each expert panel is tainted, at least to a degree, by its own special interests. Conflicting guidelines make it hard for health care consumers to figure out who to believe.
For example, several days ago the United States Preventive Services Task Force (USPSTF) came out with its final guideline on using PSA for the purpose of screening for prostate cancer. The task force recommended against using the test for screening healthy men, giving the screening test a D level rating (not recommended).
What is the USPSTF?
The U.S. Preventive Services Task Force (USPSTF), first convened by the U.S. Public Health Service in 1984, and since 1998 sponsored by the Agency for Healthcare Research and Quality (AHRQ), is the leading independent panel of private-sector experts in prevention and primary care. The USPSTF conducts rigorous, impartial assessments of the scientific evidence for the effectiveness of a broad range of clinical preventive services, including screening, counseling, and preventive medications. Its recommendations are considered the "gold standard" for clinical preventive services.
As a general internist I was indoctrinated
to trust the USPSTF with a degree of allegiance that rivals my commitment to the
University of Michigan Wolverines (my alma mater). Nonetheless, there are other expert opinions
that I also pay attention to. In the
case of PSA screening the American
Urological Association (AUA) continues to make a strong argument supporting
its use in screening. I discuss the debate more in my previous post: Should
Doctors Stop Using PSA to Screen for Prostate Cancer?
Another example of
conflicting opinions in medical guidelines:
Who should be screened for diabetes?
The American
Diabetes Association (ADA) recommends that all adults with a body mass
index >25 kg/m2 (overweight or obese adults) and one additional risk factor
for diabetes be screened at least every three years, and that all adults with a
BMI>25kg/m2 who are over 45 years of age be screened. In contrast, the
USPSTF recommends for screening only adults
with blood pressure greater than 135/80, a grade B (recommended) rating.
For other healthy adults, overweight or not, it advises that the evidence is
insufficient to recommend for or against screening.
These are but two examples of
the numerous medical guidelines and recommendations that conflict: who should be screened for HIV, whether women
ages 40 to 50 should be screened routinely for breast cancer with mammograms, how
often women over 50 should be screened with mammograms, how often women under
30 should have a pap smear, whether women need an annual pelvic exam, whether
women need an annual breast exam, and at what age screening for colon cancer
with colonoscopy should be discontinued.
The ADA, the USPSTF, the CDC, the
American College of Obstetrics and Gynecology (ACOG), the ACS, the AUA, the
American Heart Association and American College of Cardiology—along with
numerous other professional societies and expert groups have not reached
consensus on various matters.
Primary care doctors, as a
group, have largely been supportive of proposed measures to reduce medical “waste”—including
“unnecessary” tests and procedures that promise to bankrupt Medicare if they
continue to go unchecked. In turn we stand to benefit from proposals to
re-organize health care delivery and to strengthen primary care--the Medical Home
Model, which may channel additional funds toward primary care. In comparison to
specialists, primary care physicians have suffered in recent decades, with reimbursement
policies that favor physicians who do procedures, as opposed to those who primarily
talk to patients for a living. We have
been historically under-represented in the American Medical Association, the
largest physician’s professional group in our country. I am part of the American College of Physicians (ACP), a national organization of
internists — physicians who specialize in the prevention, detection and
treatment of illnesses in adults--but recognize that we also have bias—currently, in my view, a growing skepticism of tests
and procedures, which in many ways is overdue. Yet I
would wager that it’s a sentiment that primary care physicians find easier to
rally behind than do many specialists, whose interests are more likely to be
threatened by changes to reimbursement policy.
Who does one believe? Professional
guidelines are likely to shape what is covered by Medicare and private health
insurance. If you’re a gynecologist you might trust ACOG, if you’re a primary
care doctor, the USPSTF or the ACP, a urologist, the American Urological Association--the
politics of medicine are as real as the patients that we treat. Moreover, advocacy
groups, such as the Susan G. Komen Foundation and Planned Parenthood, play a
role in shaping public opinion, which no doubt can also influence the opinion
of even “expert panels,” afraid to anger
these factions.
If you are a medical
professional it’s important to be aware of where guidelines conflict and to
avoid reflexively supporting one own expert panels. Even better (though more difficult), read
through the original data. If you’re a patient, sometimes it’s good to get the
opinion of both a specialist and a generalist in these matters—each can be
equally valid and it can help one see both the trees and the forest.